Source code for the ESTIMATE algorithm: Estimate of Stromal and Immune Cells in Malignant Tumor Tissues from Expression Data (https://doi.org/10.1038/ncomms3612) Source: http://r-forge.r-project.org/projects/estimate/ Copyright: 2013-2022, MD Anderson Cancer Center (MDACC) License: GPL-2

Source code adapted from: http://download.r-forge.r-project.org/bin/windows/contrib/3.3/estimate_1.0.13.zip

deconvolute_estimate(gene_expression_matrix)

Arguments

gene_expression_matrix

a m x n matrix with m genes and n samples

Details

ESTIMATE algortihm: This function computes stromal, immune, and ESTIMATE scores per sample using gene expression data, through GSEA. The ESTIMATE score is used to compute an estimate of the tumor purity Warning: The tumor purity estimation was originally intended only for microarray affymetrix data